Oliceridine

Uses

  • Management of acute severe pain

Adverse Effects

Considerations for PT

  1. Consider risk of hypoxia and potential impact on exercise tolerance.Consider risk of hypoxia and potential impact on exercise tolerance.
  2. Consider risk of medication-related back pain and potential impact on exercise tolerance. Consider risk of medication-related back pain and potential impact on exercise tolerance.
  3. Consider risk of dizziness and drowsiness and potential impact on falls risk.Consider risk of dizziness and drowsiness and potential impact on falls risk.
  4. Consider risk of sedated state and potential impact on ability to engage with physiotherapeutic assessment and treatment. Consider risk of sedated state and potential impact on ability to engage with physiotherapeutic assessment and treatment.

Route of Administration

  1. Intravenous (IV)Intravenous (IV)

Mechanism of Action

Binds to opioid receptors to induce analgesia, works with less opioid-related adverse events than other opioids.

Drug Dynamics

Time to Peak Effect

6 minutes to 12 minutes

Duration of Action

1 hour to 3 hours

Time to Onset

1 minute to 5 minutes

Last updated: April 24, 2026