Diflunisal

Uses

  • Treatment of osteoarthritis and rheumatoid arthritis
  • Treatment of mild to moderate pain

Adverse Effects

Considerations for PT

  1. Consider timing for pain relief prior to Physiotherapy intervention.Consider timing for pain relief prior to Physiotherapy intervention.
  2. Minimal relevant common adverse effects. Monitor for any symptoms of rare adverse effects as appropriate.

Route of Administration

  1. Oral

Mechanism of Action

Decreases production of prostaglandins, resulting in decreased fever, pain, and inflammation.

Drug Dynamics

Time to Peak Effect

2 hours to 3 hours

Duration of Action

8 hours to 12 hours

Resources

*Some links accessed via VCH Intranet

Last updated: July 15, 2026