Ketorolac (systemic)

Trade Names: Toradol, MINT-Ketorolac, Mar-Ketorolac, JAMP Ketorolac, APO-Ketorolac, ALTI-Ketorolac

Uses

  • Short-term (<5 days) management of acute pain
  • Acute treatment of severe migraine

Adverse Effects

Considerations for PT

  1. Consider timing for pain relief prior to Physiotherapy intervention.Consider timing for pain relief prior to Physiotherapy intervention.
  2. Minimal relevant common adverse effects. Monitor for any symptoms of rare adverse effects as appropriate.

Route of Administration

  1. Intramuscular (IM)Intramuscular (IM)
  2. Intravenous (IV)Intravenous (IV)
  3. Oral

Mechanism of Action

Inhibits production of prostaglandins, resulting in decreased fever, pain, and/or inflammation.

Drug Dynamics

Time to Peak Effect

1 hour to 2 hours

Duration of Action

4 hours to 6 hours

Time to Onset

10 minutes to 30 minutes

Resources

*Some links accessed via VCH Intranet

Last updated: July 16, 2026